• Opioid antagonist
  • HCP-administered
  • Once-monthly injectable
  • Used with counseling
  • Non-addictive
  • Has no street value
  • Non-narcotic
  • Requires detox

What is VIVITRol

VIVITROL is a prescription injectable medicine used to:

  • Treat alcohol dependence. You should stop drinking before starting VIVITROL.
  • Prevent relapse to opioid dependence, after opioid detoxification. You must stop taking opioids before you start receiving VIVITROL. 

VIVITROL is an antagonist or blocking medication:

  • Antagonists attach to opioid receptors, but do not cause the release of dopamine. They are non-addictive and do not lead to physical dependence. Antagonists create a barrier that blocks opioid molecules from attaching to opioid receptors. VIVITROL blocks opioid receptors in the brain for one month at a time, helping patients to prevent relapse to opioid dependence, following detox, while they focus on counseling. Patients must detox before starting Vivitrol.
  • Vivitrol is not right for everyone. Discuss all benefits and risks with a doctor.
  • Before starting Vivitrol, you must be opioid-free for a minimum of 7-14 days to avoid sudden opioid withdrawal.To be effective, VIVITROL must be used with other alcohol or drug recovery programs such as counseling.



  1. Kosten TR, George TP. The neurobiology of opioid dependence: implications for treatment | Sci Pract Perspect. 2002;1(1):13-20.
  2. VIVITROL [prescribing information]. Waltham, MA: Alkermes, Inc; rev December 2015.